AN OLD WOMAN IS MURDERED in Little Italy by a hit and run driver. The old womans family begins a vendetta against a Mafia family. People start dying. The Mafia Boss finally asks a private eye, James Dunne, for help. Dunne gets caught between the Mafia and a family vendetta as his office is bombed and he is accused of murder. The detective has a hard time staying alive let alone learning who killed Signora Palmari.